It may harm an unborn baby. If you miss a dose of Cogentin, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. Check with your doctor right away if you or your child have bluish lips or skin; chest pain; difficulty with breathing; a fast, pounding or irregular heartbeat or pulse; shortness of breath; or muscle stiffness after receiving fentanyl. But benzodiazepines carry serious risks of physical and overdose.
Trazodone may enhance the response to alcohol, barbiturates, and other CNS depressants. Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures. If anyone has any advice or suggestions please let me know.
The is the hollow organ in the lower that stores urine. As the bladder fills, muscles in its walls relax so that it can expand. As the bladder empties during urination, the muscles contract to squeeze the urine out through the urethra. Everyone is talking about how they would do anything to get rid of it. I am surprised that know one has posted any results. Kaieilin says you will notice the difference in 2 days, wow! Vistaril included sufficient numbers of subjects aged 65 and over to define a difference in response from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function and of concomitant disease or other drug therapy.
Alprazolam may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Do not stop taking this medication without consulting your doctor. Be sure to tell your doctor about all health conditions and all drugs that you're using, including prescription, over-the-counter, and complementary medicines. If your doctor prescribes sleeping pills, he or she needs to ensure that they won't interact with other drugs or worsen any medical problems. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.
It is unknown if this medication passes into milk. Monitor blood pressure and pulse when reducing the dose or discontinuing the drug. Taper the daily dose in decrements of no more than 1 mg every 3 to 7 days to avoid rebound hypertension. Older adults may be more sensitive to the side effects of this drug, especially the risk for clots. All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases. Lurasidone helps you to think more clearly, feel less nervous, and take part in everyday life. The dosage is based on your age, medical condition, and response to treatment. In children, the dosage may also be based on weight. Do not increase your dose or take this medication more often than directed. It really didn't have a decent affect after taking it for about 6 months. They increased the dose by adding that I could also take it PRN. Soon I discovered that it was not working too well about 6 months later. My new prescribing physician let me know that taking Vistaril every day at the same time of day was not as effective as just taking it PRN. Check your pressure regularly and tell your doctor if the results are high. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use fentanyl injection only for the indication prescribed. Get emergency medical help if you have signs of an allergic reaction to Veramyst: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Do not use alprazolam if you are pregnant. This medicine can cause birth defects or life-threatening withdrawal symptoms in a newborn.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your or local waste disposal company. Your muscle control and coordination may be affected. This may not be a complete list of all interactions that may occur. Ask your health care provider if Cogentin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. In patients who have a history of syncope or may have a condition that predisposes them to syncope, such as hypotension, orthostatic hypotension, bradycardia, or dehydration, advise patients to avoid becoming dehydrated or overheated. Monitor blood pressure and heart rate, and adjust dosages accordingly in patients treated concomitantly with antihypertensives or other drugs that can reduce blood pressure or heart rate or increase the risk of syncope. Dizziness and drowsiness can increase the risk of falling. In studies in juvenile rats, guanfacine alone produced a slight delay in sexual maturation in males and females at 2 to 3 times the maximum recommended human dose MRHD. Guanfacine in combination with methylphenidate produced a slight delay in sexual maturation and decreased growth as measured by a decrease in bone length in males at a dose of guanfacine comparable to the MRHD and a dose of methylphenidate approximately 4 times the MRHD. atorvastatin
However, there is substantial evidence from placebo-controlled maintenance trials in adults with depression that the use of antidepressants can delay the recurrence of depression. To be sure Veramyst is not causing harmful effects on your nose or sinuses, your doctor may need to check your progress on a regular basis. It is dangerous to purchase alprazolam on the Internet or from vendors outside the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. This medication is the long-acting form of haloperidol. It is injected deep into a muscle usually the buttocks by a professional. Your first dose may be divided and given in separate injections given 3-7 days apart. After your doctor has found the best dose for you, this medication is usually given once every 3-4 weeks. Your dosage is based on your condition and response to therapy. Swallow tablets whole. Do not crush, chew, or break tablets because this will increase the rate of guanfacine release. Ask your doctor if you should have regular skin exams. Get up when you feel you can. Do not give any over-the-counter OTC and medicine to a baby or child under 4 years of age. For the past few years I have had had excess mucus and phlegm in the back of my throat. I can feel it there, and I can hack it up and usually get a thick, clear, mucus that I have to spit out or swallow. It is gross. I cough a lot during the morning and at night, and from time to time throughout the day. I try not to clear my throat too severely during work because it is disruptive and disgusting. My husband gets tired of me clearing my throat all the time, and so do I. It affects the way I talk, causing my voice to be hoarse all the time and I feel like it affects my ability to communicate professionally at work as my voice is not strong and clear. Drying out the membranes will irritate them further. Do Over-the-Counter Medicines Work? This information should not be used to decide whether or not to take Cogentin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Cogentin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Cogentin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Cogentin. Clotrimazole given orally to mice from nine weeks before mating through weaning at a dose 120 times the human dose was associated with impairment of mating, decreased number of viable young, and decreased survival to weaning. No effects were observed at 60 times the human dose. When the drug was given to rats during a similar time period at 50 times the human dose, there was a slight decrease in the number of pups per litter and decreased pup viability. The plasma half-life is about 3 hours. Librium clorazepate Tranxene diazepam Valium lorazepam Ativan or oxazepam Serax. Patients should be monitored for withdrawal symptoms when discontinuing therapy. nusp.info bentyl
This medicine may cause some people to become drowsy or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising. Some antihistamines are more likely to cause drowsiness than others. Imaging tests. A CT or MRI scan is used to take detailed images of the bladder, which are sent to a computer screen. Your doctor may inject a special dye to help the bladder show up more clearly. IVP is a series of X-rays taken of the kidneys, ureters, and bladder using a contrast dye to highlight these organs. You won't be alert, so these activities can become dangerous. 8. Don't increase the dosage that your doctor prescribed. Side effects reported with the administration of Vistaril are usually mild and transitory in nature. The mutagenic potential of ammonium lactate cream was evaluated in the Ames assay and in the mouse in vivo micronucleus assay, both of which were negative. The safety and efficacy of the prophylactic use of clotrimazole troches in children have not been established. Keep Trazodone hydrochloride tablets and all medicines out of the reach of children. Before using hydroxyzine, tell your doctor if you regularly use other medicines that make you sleepy such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety. They can add to sleepiness caused by hydroxyzine. Cyclizine may be taken with or without food. More than 1 in 3 people in America have tried at one point in their lives. Use Desyrel as directed by your doctor. Check the label on the medicine for exact dosing instructions. Check the labels on all your medicines such as or -and-cold products because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using fluvoxamine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain problems , slow heartbeat, QT prolongation in the family history of certain heart problems QT prolongation in the EKG, sudden cardiac death. cheap minomycin online store
What should I discuss with my healthcare provider before taking hydroxyzine Vistaril? This medication takes a while to start working, so you will need to continue to take your other medication by until your doctor tells you to stop. The topical treatment of CD-1 mice with 12%, 21% or 30% ammonium lactate formulations for two years did not produce a significant increase in dermal or systemic tumors in the absence of increased exposure to ultraviolet radiation. Continued 7. Don't drive a car or operate machinery after taking any kind of sleep product. In the monotherapy trials Studies 1 and 2 subgroup analyses were performed to identify any differences in response based on gender or age 6-12 vs. 13-17. Analyses of the primary outcome did not suggest any differential responsiveness on the basis of gender. Analyses by age revealed a statistically significant treatment effect only in the 6-12 age subgroup. Due to the relatively small proportion of adolescent patients ages 13-17 enrolled into these studies approximately 25% these data may not have been sufficient to demonstrate efficacy in the adolescent patients. can i buy aprovel in stores
Consideration should be given to changing the therapeutic regimen, including possibly discontinuing the medication, in patients whose depression is persistently worse, or who are experiencing emergent suicidality or symptoms that might be precursors to worsening depression or suicidality, especially if these symptoms are severe, abrupt in onset, or were not part of the patient's presenting symptoms. Consult WARNINGS section for additional precautions. Get emergency medical help if you have any signs of an allergic reaction to fentanyl: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Trazodone hydrochloride tablets, 150 mg, contain the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, crospovidone, magnesium stearate, and microcrystalline cellulose. Trazodone antagonizes alpha 1-adrenergic receptors, a property which may be associated with postural hypotension. Ensure an adequate airway, oxygenation and ventilation. Monitor cardiac rhythm and vital signs. It is not known whether Veramyst will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant or plan to become pregnant. It is not known whether hydroxyzine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. To reduce your risk ofside effects from such as dizziness get up slowly when rising from a sitting or lying position. Ziprasidone may cause a condition that affects the rhythm QT prolongation. Decreases in blood pressure and heart rate were usually modest and asymptomatic; however, hypotension and bradycardia can occur. Cystoscopy. The doctor inserts a thin, lighted tube called a cystoscope into the bladder. During the test, the doctor can remove tissue samples from the bladder to be checked in the lab for cancer biopsy. Bladder washings may also be performed to check for the presence of cancer cells. A procedure called flourescence cystoscopy is another way doctors can check for cancer. You will fell different in just 2 days by combine using foot water bath and saline nasal wash. Post your result!
If you do not take the same dose each day or if you take this medication every other day, ask your doctor or what you should do if you miss a dose. HOW TO USE: Take this medication by mouth with or without food as directed by your doctor, usually three or four times daily. This information is generalized and not intended as specific medical advice. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Cyclizine may cause drowsiness or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to cyclizine. Using cyclizine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks. If your symptoms do not improve or if they become worse, check with your doctor. How should I take alprazolam? Clinical studies in patients with preexisting cardiac disease indicate that Trazodone hydrochloride may be arrhythmogenic in some patients in that population. Arrhythmias identified include isolated PVCs, ventricular couplets, tachycardia with syncope, and torsades de pointes. Postmarketing events have been reported at doses of 100 mg or less with the immediate-release form of Trazodone. Do not use hydroxyzine without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. Avoid doing things that may cause you to overheat, such as hard work or in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. If you overheat, quickly look for a place to cool down and rest. anafranil
Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; black, tarry, or bloody stools; bloody or dark urine; chest pain; decreased coordination; decreased sexual desire or ability; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; new or worsening agitation, anxiety, depression, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, trouble sleeping, or inability to sit still; prolonged, inappropriate, or painful erections; seizures; severe or persistent dizziness or tiredness; shortness of breath; speech problems; suicidal thoughts or actions; swelling of the hands, ankles, or feet; symptoms of low blood sodium levels eg, confusion, persistent headache, trouble concentrating, memory problems, weakness, unsteadiness, sluggishness, personality changes; tremor; unusual bruising or bleeding; unusual weight changes; vomit that looks like coffee grounds; yellowing of the eyes or skin. Trazodone hydrochloride has been shown to cause increased fetal resorption and other adverse effects on the fetus in two studies using the rat when given at dose levels approximately 30 to 50 times the proposed maximum human dose. There was also an increase in congenital anomalies in one of three rabbit studies at approximately 15 to 50 times the maximum human dose. There are no adequate and well-controlled studies in pregnant women. Trazodone hydrochloride should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It decreases your 's response to various diseases to reduce symptoms such as swelling, pain, and allergic-type reactions. Trazodone is 89 to 95% protein bound in vitro at concentrations attained with therapeutic doses in humans. Antihistamines may cause dryness of the mouth, nose, and throat. If your doctor has prescribed this medication, take it as directed, usually once daily. best price topiramate with coupon
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. If you have any questions about Desyrel, please talk with your doctor, pharmacist, or other health care provider. Do not store in the bathroom. Keep all medicines away from children and pets. Researchers do know that it blocks some of the chemicals in your that react with nicotine to make you feel good when you smoke. This will reduce cravings and ease other withdrawal symptoms. Discuss the risks and benefits with your doctor. Liquid products may contain sugar. Your doctor or nurse will let you know what to do the night before and the day of the procedure. LPR, even achalasia. Just keep researching and trying new things. I hope all of you get better and find your relief. What are the ingredients in Trazodone hydrochloride tablets? You may not try this, but I will suggest it anyway. I will get right to the point. After an especially bad fit of trying to clear my throat which has been a worsening problem over several years, I took a Bio-K. It's a small yogurt sized serving of a highly potent probiotic that you can only purchase at health food or vitamin stores. Probiotics are over-hyped and the ones at grocery stores are useless. My wife has been taking Bio-K for several years to lessen her symptoms of diverticulitis and it works wonders for her. She asked me to try one and I knew that it just would not help. I let it go down my throat slowly to give it a good coat. I haven't had to clear my throat once all afternoon. Therefore, before using haloperidol, report all medications you are currently using to your doctor or pharmacist. No fatal overdoses of guanfacine have been reported in published literature. Lamotrigine is known as an anticonvulsant or antiepileptic drug. Also, in some persons histamine can close up the bronchial tubes air passages of the lungs and make breathing difficult. What are the possible side effects of Trazodone hydrochloride tablets? Consequently, the extended use of this product is not recommended. is there a generic equivalent for sibutramine
Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. One or two capsules every four hours. Healthy eating helps a lot. The best food I had was Thai food. You should not receive this medicine if you are allergic to fentanyl or other narcotic pain medicines. It is not known whether fentanyl passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Trazodone should be considered. Take Diclegis exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Hydroxyzine may cause a condition that affects the rhythm QT prolongation. Vistaril hydroxyzine pamoate is an antihistamine with anticholinergic drying and sedative properties used as a sedative to treat and tension. Vistaril is also used together with other medications given for anesthesia. Your doctor may increase the dose gradually later if needed. Side effects may go away after you take the medicine for a while. Compare Vistaril Prices - GoodRx", "side_effects_page": "Vistaril Side Effects, Information and Pricing - GoodRx", "medicare_seo_page": "Vistaril Medicare Coverage and Co-Pay Details - GoodRx", "price_page": "Vistaril Prices and Vistaril Coupons - GoodRx", "info_page": "What is Vistaril? Guanfacine is a known antihypertensive agent. By stimulating central alpha 2A-adrenergic receptors, guanfacine reduces sympathetic nerve impulses from the vasomotor center to the heart and blood vessels. This results in a decrease in peripheral vascular resistance and a reduction in heart rate. Although torsades de pointes has not been observed with the use of Trazodone hydrochloride tablets at recommended doses in premarketing trials, experience is too limited to rule out an increased risk. However, there have been postmarketing reports of torsades de pointes with the immediate-release form of Trazodone in the presence of multiple confounding factors even at doses of 100 mg per day or less. clomiphene
There is a potential for hypotension, including orthostatic hypotension and syncope. Tell your doctor right away if you have see Side Effects section. Vistaril is not a cortical depressant, but its action may be due to a suppression of activity in certain key regions of the subcortical area of the central nervous system. Primary skeletal muscle relaxation has been demonstrated experimentally. Bronchodilator activity, and antihistaminic and analgesic effects have been demonstrated experimentally and confirmed clinically. An antiemetic effect, both by the apomorphine test and the veriloid test, has been demonstrated. Pharmacological and clinical studies indicate that hydroxyzine in therapeutic dosage does not increase gastric secretion or acidity and in most cases has mild antisecretory activity. Hydroxyzine is rapidly absorbed from the gastrointestinal tract and Vistaril's clinical effects are usually noted within 15 to 30 minutes after oral administration. What happens if I overdose Vistaril? Some medical conditions may interact with Desyrel.
If you feel drowsy after taking Trazodone hydrochloride tablets, talk to your healthcare provider. Your healthcare provider may change your dose or the time of day you take your Trazodone hydrochloride tablets. Get medical help right away, if you have any of the symptoms listed above. Constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; light-headedness when sitting up or standing; muscle aches or pains; nausea; nervousness; stomach pain; stuffy nose; tiredness. Take Trazodone hydrochloride tablets exactly as your healthcare provider tells you. Over-the-counter sleep aids may prompt side effects, too. For example, diphenhydramine, a commonly used in drug store sleep aids, can cause dizziness, memory problems, and prolonged drowsiness that lingers into the following day. How should I store Trazodone hydrochloride tablets? You may have some numbness or less feeling in part of your body if you had local or regional anesthesia. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Suicide is a known risk of depression and certain other psychiatric disorders and these disorders themselves are the strongest predictors of suicide. There has been a long standing concern, however, that antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment. Pooled analyses of short-term placebo-controlled trials of antidepressant drugs SSRIs and others showed that these drugs increase the risk of suicidal thinking and behavior suicidality in children, adolescents, and young adults ages 18 to 24 with MDD and other psychiatric disorders. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction with antidepressants compared to placebo in adults aged 65 and older. US pharmacies. Save up to 80% instantly! Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. This list is not complete and other drugs may interact with hydroxyzine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Other medications can affect the removal of lurasidone from your body, which may affect how lurasidone works. It is not known if Intuniv is safe and effective in children younger than 6 years of age. Serotonin syndrome is a possibly fatal syndrome that can be caused by Desyrel. Cogentin is usually given as an injection at your doctors office, hospital, or clinic. If you will be using Cogentin at home, a health care provider will teach you how to use it. Be sure you understand how to use Cogentin. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions. buy clavaseptin online reddit
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Store Veramyst in an upright position at room temperature, away from moisture and heat. Throw the spray bottle away after you have used 120 sprays, even if there is still medicine left in the bottle. Guanfacine was not shown to prolong the QTc interval to any clinically relevant extent. In patients receiving serotonergic drugs in combination with a monoamine oxidase inhibitor MAOI there have been reports of serious, sometimes fatal reactions including hyperthermia, rigidity, myoclonus, autonomic instability with rapid fluctuation in vital signs, and mental status changes that include extreme agitation progressing to delirium and coma. These reactions have also been reported in patients who have recently discontinued antidepressant treatment and have been started on an MAOI. Some cases presented with features resembling neuroleptic malignant syndrome. Furthermore, limited animal data on the effects of combined use of serotonergic antidepressants and MAOIs suggest that these drugs may act synergistically to elevate blood pressure and evoke behavioral excitation. Therefore, it is recommended that Trazodone hydrochloride tablets should not be used in combination with an MAOI or within 14 days of discontinuing treatment with an MAOI. Similarly, at least 14 days should be allowed after stopping Trazodone hydrochloride tablets before starting an MAOI.
Lozenges with licorice and slippery elm: They ease sore throats and from all that gunk running down the back of your throat. The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Mayo Clinic: “Marijuana Cannabis sativa. This medication comes with patient instructions for safe and effective use, and directions for priming the inhaler device. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
This may not be a complete list of all interactions that may occur. Ask your health care provider if cyclizine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. Here are 10 dos and don'ts for taking sleep medicines. Trazodone hydrochloride tablets are not a controlled substance. There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
Discuss the risks and benefits of treatment with your doctor. Do not use alprazolam if you are pregnant. This medicine can cause birth defects. Your baby could also become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine. Caution should be exercised when Trazodone is administered to a nursing woman. The following symptoms, anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia psychomotor restlessness hypomania, and mania, have been reported in adult and pediatric patients being treated with antidepressants for major depressive disorder as well as for other indications, both psychiatric and nonpsychiatric.